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https://ciane.net/id=1934

Created on : 30 Mar 2006
Modified on : 02 Nov 2018

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Bibliographical entry (without author) :

Prostaglandins for induction of second-trimester termination and intrauterine death. Review. {Chine}. Best Pract Res Clin Obstet Gynaecol. 2003 Oct;17(5):765-75.

Author(s) :

Ngai SW, Tang OS, Ho PC.

Year of publication :

2003

URL(s) :

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=…

Résumé (français)  :

Abstract (English)  :

The introduction of synthetic prostaglandin has revolutionized the treatment protocol for induction of second-trimester abortion and intrauterine death. Gemeprost is the only licensed synthetic prostaglandin analogue for second-trimester abortion in the United Kingdom. However, it is expensive and needs to be stored in a refrigerator. Misoprostol is marketed for use in the prevention and treatment of peptic ulcer. It is inexpensive and can be stored at room temperature. It has been widely used for induction of second-trimester abortion and intrauterine death. Misoprostol, 400 microg given vaginally every 3 hours, is probably the optimal regimen for second-trimester abortion. The combination of misoprostol and mifepristone significantly reduced the induction-to-abortion interval when compared with the misoprostol-only regimen. In addition, misoprostol can also be used as a cervical priming agent prior to dilatation and evacuation in second-trimester abortion.

Sumário (português)  :

Resumen (español)  :

Comments :

Argument (français) :

Le misoprostol, 400 microgrammes administrés par voie vaginale toutes les 3 heures, est probablement le moyen thérapeutique optimal pour un avortement au deuxième trimestre.

Argument (English):

Misoprostol, 400 microg given vaginally every 3 hours, is probably the optimal regimen for second-trimester abortion.

Argumento (português):

O misoprostol, 400 mcg administrado por via vaginal a cada 3 horas, é provavelmente o regime ideal para o aborto no segundo trimestre.

Argumento (español):

Keywords :

➡ prevention ; post-term pregnancy ; misoprostol (Cytotec) ; abortion ; pregnancy termination for medical reason

Author of this record :

Cécile Loup — 30 Mar 2006
➡ latest update : Marion Corbe — 02 Nov 2018