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Created on : 28 Mar 2006
Modified on : 02 Dec 2007

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Bibliographical entry (without author) :

Uterine rupture and dehiscence associated with intravaginal misoprostol cervical ripening. {USA}. J Reprod Med. 2000 Oct;45(10):823-6.

Author(s) :

Hill DA, Chez RA, Quinlan J, Fuentes A, LaCombe J.

Year of publication :


URL(s) :…

Résumé (français)  :

Abstract (English)  :

OBJECTIVE: To evaluate if the prostaglandin E1 analogue misoprostol, when used as an agent for cervical ripening, is associated with uterine rupture. STUDY DESIGN: We performed a two-year retrospective chart review to determine the incidence of uterine rupture in patients with a previous cesarean delivery undergoing cervical ripening or the induction of labor.

RESULTS: Uterine dehiscence occurred in 1 and uterine rupture occurred in 3 of 48 women with a prior cesarean delivery treated with 50 micrograms doses of intravaginal misoprostol for cervical ripening. Uterine rupture was found in 1 of 89 women who had an oxytocin infusion for induction of labor and none of the 24 patients who received intravaginal prostaglandin E2 placed for cervical ripening.

CONCLUSION: Intravaginal misoprostol appears to be associated with an increased incidence of uterine rupture when used in patients undergoing a trial of labor after cesarean.

Sumário (português)  :

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Argument (English):

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Keywords :

➡ vaginal birth after caesarean ; c-section/caesarean ; induction of labor ; ripening of cervix ; misoprostol (Cytotec) ; post-term pregnancy

Author of this record :

Cécile Loup — 28 Mar 2006
➡ latest update : Bernard Bel — 02 Dec 2007

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