Base de données - (CIANE)

Présentation de cette base de données documentaires (site du CIANE)
Actuellement 3111 fiches
➡ Chaîne YouTube (tutoriel)

https://ciane.net/id=770

Créée le : 28 May 2004
Modifiée le : 01 Dec 2007

➡ Modifier cette fiche
Ne suivez ce lien que si vous possédez un mot de passe d’éditeur !

Notice bibliographique (sans auteurs) :

Increased breath markers of oxidative stress in normal pregnancy and in preeclampsia. American Journal of Obstetrics and Gynecology 2004;190(5):1184-1190.

Auteur·e(s) :

Moretti M, Phillips M, Abouzeid A, Cataneo RN, Greenberg J.

Année de publication :

2004

URL(s) :

http://www.sciencedirect.com/science/article/B6W9P…

Résumé (français)  :

Abstract (English)  :

Objectives

The purpose of this study was to compare the intensity of oxidative stress in normal pregnancy, preeclampsia, and nonpregnant women using a breath test.

Study design

We studied primiparous women in third trimester pregnancy (38 uncomplicated, 26 with preeclampsia) and 60 nonpregnant control subjects. Volatile organic compounds (VOCs) in alveolar breath were analyzed by gas chromatography/mass spectroscopy to construct the breath methylated alkane contour (BMAC), a 3-dimensional display of abundance of C4-C20 alkanes and monomethylated alkanes.

Results

The mean volume under curve (VUC) of the BMAC was significantly higher in preeclampsia patients than in normal pregnant women (P<.003) and nonpregnant control subjects (P<.005). A predictive model employing 5 VOCs distinguished preeclampsia from uncomplicated pregnancy (sensitivity = 92.3%, specificity = 89.7%; cross-validated sensitivity = 88.5%, specificity = 79.3%).

Conclusion

A breath test significantly demonstrated greater oxidative stress in women with preeclampsia than in uncomplicated pregnancy and nonpregnant control subjects. The breath test accurately identified women with established preeclampsia, but further studies are required to determine if this test can predict the onset of disease.

Sumário (português)  :

Resumen (español)  :

Remarques :

Argument (français) :

Argument (English):

Argumento (português):

Argumento (español):

Mots-clés :

➡ dépistage ; éclampsie (pré-)

Auteur·e de cette fiche :

Cécile Loup — 28 May 2004