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Created on : 11 Feb 2004
Modified on : 02 Dec 2007

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Bibliographical entry (without author) :

An Amniotic Fluid Index 5 cm Within 7 Days of Delivery in the Third Trimester Is Not Associated with Decreasing Umbilical Arterial pH and Base Excess. Journal of Perinatology 2004;24(2):72-76.

Author(s) :

Driggers RW, Holcroft CJ, Blakemore KJ, Graham EM.

Year of publication :

2004

URL(s) :

http://www.nature.com/cgi-taf/DynaPage.taf?file=/j…

Résumé (français)  :

Abstract (English)  :

OBJECTIVE:

To determine if an amniotic fluid index (AFI) 5.0 cm within 7 days of delivery in the third trimester is associated with decreasing umbilical arterial pH and base excess.

STUDY DESIGN:

Cases for this retrospective cohort study were all pregnancies 26 weeks with intact membranes and an AFI 5.0 cm within 7 days of delivery between 11/99 and 7/02. Multiple gestations, aneuploid, and anomalous fetuses were excluded. Controls with an AFI >5.0 cm within 7 days of delivery were matched to each case within 1 week by gestational age. For a control group with a mean±SD umbilical arterial pH of 7.26±0.07 and =0.05, a sample size of 100 would have a power of 99% to detect a difference with a study group whose mean was 7.20. Data were compared using paired Student’s t-test, Mann-Whitney, Fisher’s exact, 2 and risk ratios with 95% confidence intervals.

RESULTS:

In all, 131 neonates with an AFI 5.0 cm were matched to 131 controls with an AFI >5 cm. There was no difference in gestational age (37.6±3.0, 37.7±3.0 weeks) or birth weight (2897±810, 2762±788 g). There was no difference in umbilical artery pH (7.25±0.07, 7.26±0.07) or base excess (-3.32±2.59, -2.83±2.45 mmol/l), even in small for gestational age (SGA) infants in both groups. There was no difference in the number of SGA neonates, 5-minute Apgar <7, respiratory distress syndrome, necrotizing enterocolitis, or neurologic morbidity. Linear regression showed no correlation between AFI and either umbilical arterial pH (r=-0.00047, SE=0.001, p=0.63) or base excess (r=-0.029, SE=0.037, p=0.428).

CONCLUSION:

An AFI 5.0 cm measured within 7 days of delivery in the third trimester is not associated with decreasing umbilical arterial pH and base excess.

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Resumen (español)  :

Comments :

Argument (français) :

Argument (English):

Argumento (português):

Argumento (español):

Keywords :

➡ evidence-based medicine/midwifery ; screening ; fetal distress ; morbidity

Author of this record :

Cécile Loup — 11 Feb 2004