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Criado em : 30 Jan 2004
Alterado em : 01 Dec 2007

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Nota bibliográfica (sem autor) :

A small randomised trial of low-dose aspirin in women at high risk of pre-eclampsia. European Journal of Obstetrics & Gynecology and Reproductive Biology 2004;112(2):142-144

Autores :

Chiaffarino F, Parazzini F, aladini D, Acaia B, Ossola W, Marozio L, Facchinetti F, Del Giudice A.

Ano de publicação :

2004

URL(s) :

http://www.sciencedirect.com/science?_ob=ArticleUR…

Résumé (français)  :

Abstract (English)  :

OBJECTIVE: To determine if aspirin (ASA) therapy reduces the incidence of pre-eclampsia in women at high risk of this condition.
STUDY DESIGN : Randomised clinical trial. We recruited pregnant women with gestational age at randomisation <14 weeks, who satisfied the following criteria: chronic hypertension, history of severe pre-eclampsia or eclampsia or intrauterine growth retardation (IUGR) or intrauterine foetal death. Nineteen women in the no-treatment group and 16 in the ASA group were successfully followed up.
RESULTS: The mean birthweight was higher in the ASA group than in the no-treatment group (2790 g (S.D. 340 g) versus 2616 g (S.D. 779 g)), but the difference was not statistically significant. We found no statistically significant differences between the groups in the proportion of infants with birthweight below 2500 g (13.3% versus 29.4%) and the number of cases with pregnancy-induced hypertension (PIH)/pre-eclampsia (31.3% versus 36.8%).
CONCLUSION: These limited data give some support to the potential favourable effect of early treatment with ASA in pregnant women at risk of PIH and IUGR.

Sumário (português)  :

Resumen (español)  :

Comentários :

Ca ne merite vraiment pas le mot cle medecine factuelle …

Argument (français) :

Argument (English):

Argumento (português):

Argumento (español):

Palavras-chaves :

➡ pre-eclampsia

Autor da esta ficha :

Cécile Loup — 30 Jan 2004