A small randomised trial of low-dose aspirin in women at high risk of pre-eclampsia. European Journal of Obstetrics & Gynecology and Reproductive Biology 2004;112(2):142-144

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https://ciane.net/id=416 Created on : 30 Jan 2004 Modified on : 01 Dec 2007	➡ Modify this record Do not follow this link unless you know an editor’s password! Share: Hard
Bibliographical entry (without author) :	A small randomised trial of low-dose aspirin in women at high risk of pre-eclampsia. European Journal of Obstetrics & Gynecology and Reproductive Biology 2004;112(2):142-144
Author(s) :	Chiaffarino F, Parazzini F, aladini D, Acaia B, Ossola W, Marozio L, Facchinetti F, Del Giudice A.
Year of publication :	2004
URL(s) :	http://www.sciencedirect.com/science?_ob=ArticleUR…
Résumé (français) :
Abstract (English) :	OBJECTIVE: To determine if aspirin (ASA) therapy reduces the incidence of pre-eclampsia in women at high risk of this condition. STUDY DESIGN : Randomised clinical trial. We recruited pregnant women with gestational age at randomisation <14 weeks, who satisfied the following criteria: chronic hypertension, history of severe pre-eclampsia or eclampsia or intrauterine growth retardation (IUGR) or intrauterine foetal death. Nineteen women in the no-treatment group and 16 in the ASA group were successfully followed up. RESULTS: The mean birthweight was higher in the ASA group than in the no-treatment group (2790 g (S.D. 340 g) versus 2616 g (S.D. 779 g)), but the difference was not statistically significant. We found no statistically significant differences between the groups in the proportion of infants with birthweight below 2500 g (13.3% versus 29.4%) and the number of cases with pregnancy-induced hypertension (PIH)/pre-eclampsia (31.3% versus 36.8%). CONCLUSION: These limited data give some support to the potential favourable effect of early treatment with ASA in pregnant women at risk of PIH and IUGR.
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Comments :	Ca ne merite vraiment pas le mot cle medecine factuelle …
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Keywords :	➡ eclampsia (pre-)
Author of this record :	Cécile Loup — 30 Jan 2004

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