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Creado el : 24 May 2005
Alterado em : 02 Dec 2007

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Ficha bibliográfica (sin autores) :

Birth outcomes after prenatal exposure to antidepressant medication. Am J Obstet Gynecol. 2003 Mar;188(3):812-5.

Autores :

Hendrick V, Smith LM, Suri R, Hwang S, Haynes D, Altshuler L.

Año de publicación :

2003

URL(s) :

http://L’utilisation d’anti-dépresseurs pendant…

Résumé (français)  :

Abstract (English)  :

OBJECTIVE: The purpose of this study was to examine prospectively the incidence of congenital anomalies and neonatal complications after prenatal exposure to antidepressant medication.

STUDY DESIGN: Birth outcomes were obtained from a review of obstetric and neonatal records of 138 women who were treated with selective serotonin reuptake inhibitor antidepressant medications (SSRIs) during pregnancy.

RESULTS: The incidence of congenital anomalies in this study was 1.4%, comparable to general population rates. Rates of low birth weight and preterm births were low, occurring in 2.9% and 6.5% of births, respectively. The low birth weight infants had been exposed to relatively high doses of fluoxetine (40-80 mg/d) throughout pregnancy. Average maternal weight gain in pregnancy was comparable across the three major medication categories (fluoxetine, paroxetine, sertraline).

CONCLUSION: After prenatal use of selective serotonin reuptake inhibitor antidepressant medications, neonatal complications and congenital anomalies appear to occur within general population rates. However, maternal use of high doses of fluoxetine throughout pregnancy may be associated with a risk for low birth weight.

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Palabras claves :

➡ depresión, ansiedad ; prematuro ; psicología ; bajo peso al nacer

Autor de este registro :

Cécile Loup — 24 May 2005