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Criado em : 16 Nov 2004
Alterado em : 02 Dec 2007

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Nota bibliográfica (sem autor) :

Circulating levels of inhibin A, inhibin B and activin A in normal and intrauterine growth restricted (IUGR) fetuses. European Journal of Obstetrics & Gynecology and Reproductive Biology 2004;117(1):38-44.

Autores :

Morpurgo PS, Cetin I, Borgato S, Cortelazzi D, Nobile-DeSantis MS, Vaghi I, Beck-Peccoz P.

Ano de publicação :

2004

URL(s) :

http://www.sciencedirect.com/science?_ob=ArticleUR…

Résumé (français)  :

Abstract (English)  :

Objective: To evaluate the relationships between circulating levels of inhibin A, inhibin B and activin A, and sex, gestational age and gonadotropins in normal and pathological fetuses.

Study design: The study included 31 normal fetuses and 12 affected with intrauterine growth restriction (IUGR) of gestational age ranging 20–40 weeks.

Results: No gender difference in inhibin A and activin A levels were observed. Inhibin B levels were significantly higher in males than in females (P<0.05). Fetuses with the highest levels of inhibin A and B were found in the IUGR group that also showed activin A levels significantly higher than normal. No correlations were observed between inhibin A, inhibin B, activin A and both gonadotropins.

Conclusion: Plasma inhibin A, inhibin B and activin A are detectable in both genders during intrauterine life. The different gender pattern of inhibin B suggests that inhibin B may contribute to the assessment of the hypothalamic–pituitary–gonadal set-point at least in males.

Sumário (português)  :

Resumen (español)  :

Comentários :

Argument (français) :

Argument (English):

Argumento (português):

Argumento (español):

Palavras-chaves :

➡ fisiologia ; hormonas ; desenvolvimento do feto ; baixo peso à nascença

Autor da esta ficha :

Cécile Loup — 16 Nov 2004