Banco de dados - (CIANE)

Descrição deste banco de dados documental (Site da CIANE)
Atualmente 3111 fichas
➡ Canal do YouTube (tutorial)

https://ciane.net/id=1325

Criado em : 24 Oct 2005
Alterado em : 02 Dec 2007

➡ Modificar esta ficha
Siga este link somente se você tiver um palavra chave de editor!

Nota bibliográfica (sem autor) :

Screening test for preeclampsia through assessment of uteroplacental blood flow and biochemical markers of oxidative stress and endothelial dysfunction.{Chili}. Am J Obstet Gynecol. 2005 Oct;193(4):1486-91.

Autores :

Parra M, Rodrigo R, Barja P, Bosco C, Fernandez V, Munoz H, Soto-Chacon E.

Ano de publicação :

2005

URL(s) :

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=…

Résumé (français)  :

Abstract (English)  :

OBJECTIVE: This study was undertaken to evaluate whether screening through a uterine artery (UtA) Doppler and biochemical markers of oxidative stress and endothelial dysfunction predict preeclampsia.

STUDY DESIGN: UtA Doppler was performed at 11 to 14 and 22 to 25 weeks on 1447 asymptomatic pregnant women. Oxidative stress, endothelial dysfunction, and antiangiogenic state were assessed in women who later developed preeclampsia and normotensive controls.

RESULTS: There was a significantly increased of UtA pulsatility index (PI), plasma levels of soluble fms-like tyrosine kinase 1 (sFlt1), PAI-1/PAI-2 ratio, and F-2 isoprostane in women who subsequently developed preeclampsia compared with control pregnancies. Multivariate logistic regression showed that increased UtA PI performed at 23 weeks was the best predictor for preeclampsia.

CONCLUSION: This study demonstrates early changes in markers of impaired placentation, antiangiogenic state, oxidative stress, and endothelial dysfunction suggesting that these derangements may play a role in the pathogenesis of preeclampsia. Our data point to UtA as the best test to predict preeclampsia at 23 weeks of gestation.

Sumário (português)  :

Resumen (español)  :

Comentários :

Argument (français) :

L’echo doppler sur les artères utérines autour de 23 semaines permettrait de prédire assez surement les risques de pré-éclampsie.

Argument (English):

Argumento (português):

Argumento (español):

Palavras-chaves :

➡ medicina baseada em evidências ; diagnóstico pré-natal ; pre-eclampsia

Autor da esta ficha :

Cécile Loup — 24 Oct 2005